European Journal of Oncology Nursing
Volume 15, Issue 2 , Pages 95-102 , April 2011

Symptom prevalence and changes of symptoms over ten days in hospitalized patients with advanced cancer: A descriptive study

  • Elisabeth Spichiger

      Affiliations

    • Institute of Nursing Science, University of Basel, Bernoullistrasse 28, 4056 Basel, Switzerland
    • Inselspital Bern University Hospital, 3010 Bern, Switzerland
    • Corresponding Author InformationCorresponding author. Institute of Nursing Science, University of Basel, Bernoullistrasse 28, 4056 Basel, Switzerland. Tel.: +41 31 371 42 88; fax: +41 61 267 09 55.
  • ,
  • Christa Müller-Fröhlich

      Affiliations

    • Institute of Nursing Science, University of Basel, Bernoullistrasse 28, 4056 Basel, Switzerland
  • ,
  • Kris Denhaerynck

      Affiliations

    • Institute of Nursing Science, University of Basel, Bernoullistrasse 28, 4056 Basel, Switzerland
  • ,
  • Hansruedi Stoll

      Affiliations

    • Oncology Unit, University Hospital Basel, Petersgraben 4, 4031 Basel, Switzerland
  • ,
  • Virpi Hantikainen

      Affiliations

    • Inselspital Bern University Hospital, 3010 Bern, Switzerland
  • ,
  • Marylin Dodd

      Affiliations

    • School of Nursing, University of California San Francisco, 2 Koret Way, San Francisco, CA 94143, United States

References 

  1. Bladgen SP, Charman SC, Sharples LD, Magee LRA, Gilligan D. Performance status score: do patients and their oncologists agree?. British Journal of Cancer. 2003;89:1022–1027
  2. Borgsteede SD, Deliens L, Beentjes B, Schellevis F, Stalman WAB, Van Eijk JTM, et al. Symptoms in patients receiving palliative care: a study on patient-physician encounters in general practice. Journal of Palliative Medicine. 2007;21:417–423
  3. Braiteh F, El Osta B, Palmer JL, Reddy SK, Bruera E. Characteristics, findings, and outcomes of palliative care inpatient consultations at a comprehensive cancer center. Journal of Palliative Medicine. 2007;10:948–955
  4. Breitbart W, Chochinov HM, Passik SD. Psychiatric symptoms in palliative medicine. In:  Doyle D,  Hanks G,  Cherny N,  Calman K editor. Oxford Textbook of Palliative Medicine. third ed.. Oxford: Oxford University Press; 2005;p. 746–771
  5. Chang VT, Hwang SS, Feuerman M, Kasimis BS. Symptom and quality of life survey of medical oncology patients at a veterans affairs medical center: a role for symptom assessment. Cancer. 2000;88:1175–1183
  6. Chang VT, Hwand S, Kasimis B. Longitudinal documentation of cancer pain management outcomes: a pilot study at a VA medical center. Journal of Pain and Symptom Management. 2002;24:494–505
  7. Chen ML, Chang HK. Physical symptom profiles of depressed and nondepressed patients with cancer. Journal of Palliative Medicine. 2004;18:712–718
  8. Chiu TY, Hu WY, Chen CY. Prevalence and severity of symptoms in terminal cancer patients: a study in Taiwan. Supportive Care in Cancer. 2000;8:311–313
  9. Cleeland CS. Cancer-related symptoms. Seminars in Radiation Oncology. 2000;10:175–190
  10. Cleeland CS, Mendoza TR, Wang XS, Chou C, Harle MT, Morrissey M, et al. Assessing symptom distress in cancer patients: the M.D. Anderson symptom inventory. Cancer. 2000;89:1634–1646
  11. Corless IB, Nicholas PK, Nokes KM. Issues in cross-cultural quality-of-life research. Journal of Nursing Scholarship. 2001;33:15–20
  12. Degner LF, Sloan JA. Symptom distress in newly diagnosed ambulatory cancer patients and as a predictor of survival in lung cancer. Journal of Pain and Symptom Management. 1995;10:423–431
  13. Dodd M, Janson S, Facione N, Faucett J, Froelicher ES, Humphreys J, et al. Advancing the science of symptom management. Journal of Advanced Nursing. 2001;33:668–676
  14. Donnelly S, Walsh D. The symptoms of advanced cancer. Seminars in Oncology. 1995;22(Suppl):67–72
  15. Dumitrescu L, Van den Heuvel-Olaroiu M, Van den Heuel WJA. Changes in symptoms and pain intensity of cancer patients after enrollment of palliative care at home. Journal of Pain and Symptom Management. 2007;34:488–496
  16. Eastern Cooperative Oncology Group . ECOG performance status. Retrieved 10.1.2005, from http://www.ecog.org/general/perf_stat.html2000;
  17. Echteld MA, Deliens L, Ooms ME, Ribbe MW. Palliative care units in the Netherlands: changes in patients’ functional status and symptoms. Journal of Pain and Symptom Management. 2004;28:233–243
  18. Elsayem A, Swint K, Fisch MJ, Palmer JL, Reddy S, Walker P, et al. Palliative care inpatient service in a comprehensive cancer center: clinical and financial outcomes. Journal of Clinical Oncology. 2004;22:2008–2014
  19. Farrar JT, Young JP, LaMoreaux L, Werth JL, Poole RM. Clinical importance of change in chronic pain intensity measured on an 11-point numerical pain rating scale. Pain. 2001;94:149–158
  20. Flaherty JA. Developing instruments for cross-cultural psychiatric research. The Journal of Nervous and Mental Disease. 1988;176:257–263
  21. Follwell M, Burman D, Le LW, Wakimoto K, Seccareccia D, Bryson J, et al. Phase II of an outpatient palliative care intervention in patients with metastatic cancer. Journal of Clinical Oncology. 2009;27:206–213
  22. Gift AG, Jablonski A, Stommel M, Given CW. Symptom clusters in elderly patients with lung cancer. Oncology Nursing Forum. 2004;31:203–212
  23. Hann DM, Jacobsen PB, Martin SC, Kronish LE, Azzarello LM, Fields KK. Quality of life following bone marrow transplantation for breast cancer: a comparative study. Bone Marrow Transplantation. 1997;19:257–264
  24. Herrmann C, Buss U, Snaith RP. HADS-D hospital anxiety and depression scale - deutsche version. Ein Fragebogen zur Erfassung von Angst und Depression in der somatischen Medizin Huber, Bern: Testdokumentation und Handanweisung; 1995;
  25. Holzemer WL, Hudson A, Kirksey KM, Hamilton MJ, Bakken S. The revised sign and symptom check-list for HIV (SSC-HIVrev.). Journal of the Association of Nurses in AIDS Care. 2001;12:60–70
  26. Jones PS, Lee JW, Phillips LR, Zhang XE, Jaceldo KB. An adaptation of Brislin’s translation model for cross-cultural research. Nursing Research. 2001;50:300–304
  27. Kurtz ME, Kurtz JC, Given CC, Given B. Concordance of cancer patient and caregiver symptom reports. Cancer Practice. 1996;4:185–190
  28. Kwon YC, Yun YH, Lee KH, Son KY, Park SM, Chang YJ, et al. Symptoms in the lives of terminal cancer patients: which is the most important?. Oncology. 2006;71:69–76
  29. Larson PJ, Uchinuno A, Izumi S, Kawano A, Takemoto A, Shigeno M, et al. An integrated approach to symptom management. Nursing & Health Sciences. 1999;1:203–210
  30. Lidstone V, Butters E, Seed PT, Sinnott C, Beynon T, Richards M. Symptoms and concerns amongst cancer outpatients: identifying the need for specialist palliative care. Journal of Palliative Medicine. 2003;17:588–595
  31. Lo RSK, Ding A, Chung TK, Woo J. Prospective study of symptom control in 133 cases of palliative care inpatients in Shatin hospital. Journal of Palliative Medicine. 1999;13:335–340
  32. Lobchuk MM, Degner LF. Symptom experiences: perceptual accuracy between advanced-stage cancer patients and family caregivers in the home care setting. Journal of Clinical Oncology. 2002;20:3495–3507
  33. Mercadante S, Casuccio A, Fulfaro F. The course of symptom frequency and intensity in advanced cancer patients followed at home. Journal of Pain and Symptom Management. 2000;20:104–112
  34. Meuser T, Pietruck C, Radbruch L, Stute P, Lehmann KA, Grond S. Symptoms during cancer pain treatment following WHO-guidelines: a longitudinal follow-up study of symptom prevalence, severity and etiology. Pain. 2001;93:247–257
  35. Miaskowski C, Dodd M, West C, Schuhmacher K, Paul SM, Tripathy D, et al. Randomized clinical trial of the effectiveness of a self-care intervention to improve cancer pain management. Journal of Clinical Oncology. 2004;22:1713–1720
  36. Mock V, Atkinson A, Barsevick A, Blackwel S, Cella D, Cimprich B, et al. Cancer-related Fatigue. Practice Guidelines in Oncology Version 1. Retrieved 07.09.2004, from 2004;http://www.nccn.org/professionals/physician_gls/PDF/fatigue.pdf
  37. Modonesi C, Scarpi E, Maltoni M, Derni S, Fabbri L, Martini F, et al. Impact of palliative care unit admission on symptom control evaluated by the Edmonton Symptom Assessment System. Journal of Pain and Symptom Management. 2005;30:367–373
  38. Nekolaichuk CL, Bruera E, Spachynski K, MacEachern T, Hanson J, Maguire TO. A comparison of patient and proxy symptom assessments in advanced cancer patients. Journal of Palliative Medicine. 1999;13:311–323
  39. Oken MM, Creech RH, Tormey DC, Horton J, Davis TE, McFadden ET, et al. Toxicity and response criteria of the eastern cooperative oncology group. American Journal of Clinical Oncology. 1982;5:649–655
  40. Patrick DL, Ferketich SL, Frame PS, Harris JJ, Hendricks CB, Levin B, et al. National institutes of health state-of-the-science conference statement: symptom management in cancer: pain, depression, and fatigue. Journal of the National Cancer Institute. 2003;95:1110–1117July 15-17, 2002
  41. Pautex S, Berger A, Chatelain C, Herrmann F, Zulian GB. Symptom assessment in elderly cancer patients receiving palliative care. Critical Reviews in Oncology/Hematology. 2003;47:281–286
  42. Peters L, Sellick K. Quality of life of cancer patients receiving inpatient and home-based palliative care. Journal of Advanced Nursing. 2006;53:524–533
  43. Portenoy RK, Thaler HT, Kornblith AB, Lepore JM, Friedlander-Klar H, Coyle N, et al. Symptom prevalence, characteristics and distress in a cancer population. Quality of Life Research. 1994;3:183–189
  44. Portenoy RK, Thaler HT, Kornblith AB, Lepore JM, Friedlander-Klar H, Kiyasu E, et al. The memorial symptom assessment scale: an instrument for the evaluation of symptom prevalence, characteristics and distress. European Journal of Cancer. 1994;30A:1326–1336
  45. Potter J, Hami F, Bryan T, Quigley C. Symptoms in 400 patients referred to palliative care services: prevalence and patterns. Journal of Palliative Medicine. 2003;17:310–314
  46. Radbruch L, Nauck F, Ostgathe C, Elsner F, Bausewein C, Fuchs M, et al. What are the problems in palliative care? Results from a representative survey. Supportive Care in Cancer. 2003;11:442–451
  47. Reuter K. Fatigue und/oder depression? Ein Beitrag zur Konstruktvalidierung und diagnostischen Unterscheidung bei Patienten mit Tumorerkrankungen. Freiburg i. Br: Albert-Ludwigs-Universität; 2002;
  48. Reuter K, Härter M. Screening for mental disorders in cancer patients – discriminant validity of HADS and GHQ-12 assessed by standardized clinical interview. International Journal of Methods in Psychiatric Research. 2001;10:86–96
  49. Rhodes VA, McDaniel RW. The symptom experience and its impact on quality of life. In:  Yarbro CH,  Goodman M,  Fogge MH editor. Cancer Symptom Management. third ed.. London: Jones & Bartlett; 1999;p. 3–8
  50. Salminen E, Clemens KE, Syrjänen K, Salmenoja H. Needs of developing the skills of palliative care at the oncology ward. Supportive Care in Cancer. 2008;16:3–8
  51. Schuit KW, Sleijfer DT, Meijler WJ, Otter R, Schakenraad J, van den Bergh FC, et al. Symptoms and functional status of patients with disseminated cancer visiting outpatient departments. Journal of Pain and Symptom Management. 1998;16:290–297
  52. Sidani S. Symptom management. In:  Doran DM editors. Nursing-sensitive Outcomes: State of the Science. Boston: Jones and Bartlett; 2003;p. 115–175
  53. Strömgren AS, Goldschmidt D, Groenvold M, Petersen MA, Jensen PT, Pedersen L, et al. Self-assessment in cancer patients referred to palliative care: a study of feasibility and symptom epidemiology. Cancer. 2002;94:512–520
  54. Strömgren AS, Groenvold M, Sorensen A, Andersen L. Symptom recognition in advanced cancer. a comparison of nursing records against patient self-rating. Acta Anaesthesiologica Scandinavica. 2001;45:1080–1085
  55. Strömgren AS, Sjogren P, Goldschmidt D, Petersen MA, Pedersen L, Groenvold M. Symptom priority and course of symptomatology in specialized palliative care. Journal of Pain and Symptom Management. 2006;31:199–206
  56. Teunissen SC, de Graeff A, de Haes HC, Voest EE. Prognostic significance of symptoms of hospitalised advanced cancer patients. European Journal of Cancer. 2006;42:2510–2516
  57. Teunissen SC, Wesker W, Kruitwagen C, de Haes HC, Voest EE, de Graeff A. Symptom prevalence in patients with incurable cancer: a systematic review. Journal of Pain and Symptom Management. 2007;34:94–104
  58. Tranmer JE, Heyland D, Dudgeon D, Groll D, Squires-Graham M, Coulson K. Measuring the Symptom experience of seriously ill cancer and noncancer hospitalized patients near the end of life with the memorial symptom assessment scale. Journal of Pain and Symptom Management. 2003;25:420–429
  59. Tsai JS, Wu CH, Chiu TY, Hu WY, Chen CY. Symptom patterns of advanced cancer patients in a palliative care unit. Journal of Palliative Medicine. 2006;20:617–622
  60. Vainio A, Auvinen A, Ahmedzai S, Benton TF, Walsh D, Higginson I, et al. Prevalence of symptoms among patients with advanced cancer: an international collaborative study. Journal of Pain and Symptom Management. 1996;12:3–10
  61. Walsh D, Donnelly S, Rybicki L. The symptoms of advanced cancer: relationship to age, gender, and performance status in 1000 patients. Supportive Care in Cancer. 2000;8:175–179
  62. Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Scandinavian. 1983;67:361–370
  63. Zubrod CG, Schneiderman M, Frei E, Brindley C, Gold GL, Shnider B, et al. Appraisal of mehtods for the study of chemotherapy of cancer in man: comparative therapeutic trial of nitrogen mustard and triethylene thiophosphoramide. Journal of Chronic Diseases. 1960;11:7–33

PII: S1462-3889(10)00097-9

doi: 10.1016/j.ejon.2010.06.005

European Journal of Oncology Nursing
Volume 15, Issue 2 , Pages 95-102 , April 2011