Effects of home-based exercise on exercise capacity, symptoms, and quality of life in patients with lung cancer: A meta-analysis

  • Meng Yang
    Affiliations
    State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, No. 651 Dongfengdong Road, Guangzhou, China
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  • Li Liu
    Affiliations
    State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, No. 651 Dongfengdong Road, Guangzhou, China
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  • Chun-e Gan
    Affiliations
    State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, No. 651 Dongfengdong Road, Guangzhou, China
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  • Li-hong Qiu
    Affiliations
    State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, No. 651 Dongfengdong Road, Guangzhou, China
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  • Xiao-juan Jiang
    Affiliations
    State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, No. 651 Dongfengdong Road, Guangzhou, China
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  • Xue-ting He
    Affiliations
    School of Nursing, Sun Yat-sen University, No. 74 Zhongshan Second Road, Guangzhou, China
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  • Jun-e Zhang
    Correspondence
    Corresponding author.
    Affiliations
    School of Nursing, Sun Yat-sen University, No. 74 Zhongshan Second Road, Guangzhou, China
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Published:October 24, 2020DOI:https://doi.org/10.1016/j.ejon.2020.101836

      Highlights

      • Home-based exercise significantly improves exercise capacity and quality of life of patients with lung cancer.
      • Home-based exercise can reduce lung cancer patients' cancer-related fatigue, insomnia, anxiety, depression.
      • Nurses should encourage lung cancer patients to engage in home-based exercise following their discharge from hospital.

      Abstract

      Purpose

      The aim of this study was to evaluate the effects of home-based exercise on exercise capacity, cancer-related fatigue, insomnia, pain, appetite loss, coughing, anxiety, depression, and quality of life of patients with lung cancer.

      Methods

      We conducted a search using English and Chinese databases, namely PubMed, Web of Science, Embase, ProQuest, the Cochrane Library, China National Knowledge Infrastructure (CNKI), Chinese Biomedical Literature (CBM), Wanfang Data, and China Science and Technology Journal Database (VIP) up to December 4, 2018. We selected randomized controlled trials and quasi-experimental trials that compared the effects of home-based exercise and routine guidance on exercise capacity, cancer-related fatigue, insomnia, pain, appetite loss, coughing, anxiety, depression, and quality of life of patients with lung cancer. The effect size was calculated using mean difference and 95% confidence interval, data were analyzed using the Stata version 12.0 software.

      Results

      We retrieved seven randomized controlled trials and seven quasi-experimental trials involving 694 patients in total. Home-based exercise significantly improved exercise capacity, reduced cancer-related fatigue, insomnia, anxiety, and depression, and improved quality of life (P < .05). However, it did not significantly reduce pain, appetite loss, and coughing symptoms (P > .05).

      Conclusions

      Home-based exercise is a beneficial approach to improving exercise capacity, some symptoms, and quality of life of patients with lung cancer. Home-based exercise should be routinely recommended by health professionals when patients with lung cancer are discharged from hospital.

      Keywords

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